SUZ12 Antibody (C-term)

SKU: orb106948

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Description

Rabbit polyclonal to SUZ12. Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates Lys-9 (H3K9me) and Lys-27 (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Cancer,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics,Primary Antibodies

Images & Validation

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Item 1 of 2

Tested Applications	WB
Dilution Range	WB: 1:1000
Reactivity	Human, Mouse

Key Properties

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Antibody Type	Primary Antibody
Host	Rabbit
Clonality	Polyclonal
Isotype	Rabbit IgG
Clone No.	RB42757
Immunogen	Synthetic Peptide
Target	SUZ12
Molecular Weight	83055
Conjugation	Unconjugated

Storage & Handling

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Storage	Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles
Form/Appearance	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

Alternative Names

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anti SUZ12 antibody, anti CHET9 antibody, anti JJAZ1 antibody, anti KIAA0160 antibody, anti Polycomb protein SUZ12 antibody, anti Polycomb protein SUZ12 antibody, anti Chromatin precipitated E2F target 9 protein antibody, anti Polycomb protein SUZ12 antibody, anti Joined to JAZF1 protein antibody, anti Polycomb protein SUZ12 antibody, anti Suppressor of zeste 12 protein homolog antibody

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Quick Database Links

Gene Symbol

SUZ12

UniProt

Q15022

RefSeq (Protein):NP_056170.2

UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers

Curated reference sequences for the gene transcript and protein product

Protein	NP_056170.2

Protocol Information

Western Blot (IB, immunoblot)

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