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Ponatinib (AP24534)

SKU: orb154625

Description

AP24534 is a novel, potent multi-target inhibitor of Abl, PDGFRα, VEGFR2, FGFR1 and Src with IC50 of 0.37 nM, 1.1 nM, 1.5 nM, 2.2 nM and 5.4 nM, respectively.

Research Area

Product Categories/Products/Small Molecules,Product Categories/Products/Small Molecules/Inhibitors

Images & Validation

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Key Properties

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CAS Number[943319-70-8]
MW532.56
FormulaC29H27F3N6O
SMILESCC1=C(C=C(C=C1)C(NC2=CC(C(F)(F)F)=C(C=C2)CN3CCN(CC3)C)=O)C#CC4=CN=C5N4N=CC=C5

Storage & Handling

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Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Protocol Information

Available Sizes

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1 ml x 10 mm (in DMSO)
$ 300.00
100 mg
$ 360.00
250 mg
$ 620.00
1 g
$ 1,150.00
DispatchUsually dispatched within 5-10 working days.
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