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POMC Antibody / ACTH / N-Terminal

SKU: orb385765

Description

POMC (pro-opiomelanocortin or corticotropin-lipotropin) is a 267 amino acid polypeptide hormone precursor that goes through extensive, tissue-specific posttranslational processing by convertases. POMC is cleaved into ten hormone chains named NPP, ACTH, alpha-MSH (Melanocyte Stimulating Hormone), beta-MSH, gamma-MSH, CLIP (corticotropin-like intermediary peptide), Lipotropin-beta, Lipotropin-gamma, beta-endorphin and Met-enkephalin.

Research Area

Product Categories/Products/Antibodies,Product Categories/Research Area,Product Categories/Products/Antibodies/Primary Antibodies,Epigenetics

Images & Validation

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Tested ApplicationsELISA, FACS, IF, IHC-P
Dilution RangeELISA (order BSA/sodium azide-free format for coating),Flow cytometry: 0.5-1ug/million cells,Immunofluorescence: 0.5-1ug/ml,Immunohistochemistry (FFPE): 0.5-1ug/ml for 30 min at RT
ReactivityHuman, Mouse, Rat
Application Notes
The optimal dilution of the ACTH / POMC antibody for each application should be determined by the researcher.1. View the recombinant version of this ACTH antibody.

Key Properties

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Antibody TypePrimary Antibody
HostMouse
ClonalityMonoclonal
IsotypeMouse IgG1, kappa
Clone No.57
ImmunogenAn N-terminal peptide (within AA 1-24) from the Synacthen/ACTH region of human POMC was used as the immunogen for this POMC antibody.
PurityProtein G affinity chromatography
ConjugationUnconjugated

Storage & Handling

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StorageStore the POMC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Buffer/Preservatives0.2 mg/ml in 1X PBS with 0.1 mg/ml rAlbumin (US sourced) and 0.05% sodium azide
Expiration Date12 months from date of receipt.
Hazard InformationThis POMC antibody is available for research use only.
DisclaimerFor research use only

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Quality Guarantee

Quality Guarantee

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UniProt Details

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No UniProt data available

Protocol Information

IHC-P
Immunohistochemistry Paraffin
View Protocol
FACS
Fluorescence-Activated Cell Sorting (FC, Flow cytometry)
View Protocol
IF
Immunofluorescence
View Protocol
ELISA
Enzyme-linked Immunosorbent Assay (EIA)
View Protocol

Available Sizes

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20 μg
$ 410.00
Free Secondary Antibody (20 ul)0/0

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