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Murine Cardiotrophin-1 protein

SKU: orb107700

Description

Cardiotrophin1(CT1)is a member of the cytokine family which also includes IL-6, IL-11, leukemia inhibitory factor (LIF),oncostatin M (OSM), and ciliary neurotrophic factor (CNTF). CT-1 is a pleiotropic cytokine which is expressed in various tissuesincluding the adult heart, skeletal muscle, ovary, colon, prostate and fetal lung. In addition, CT-1 which induces cardiac myocytehypertrophy in vitro can bind to and activate the ILST/gp130 receptor. Murine CT1encodes a 203 amino acid (a.a.) residueprotein that lacks a hydrophobic signal peptide. Human and murine CT1share 80 % a.a. sequence identity and exhibit crossspeciesactivity.

Images & Validation

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Tested ApplicationsHPLC, SDS-PAGE

Key Properties

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Biological OriginE.coli
TargetCardiotrophin-1
ConjugationUnconjugated
MW18.2 kDa
Purity> 95 % by SDS-PAGE and HPLC analyses
Protein SequenceLRPGDCEVCI SYLGRFYQDL KDRDVTFSPA TIENELIKFC REARGKENRL CYYIGATDDAATKIINEVSK PLAHHIPVEK ICEKLKKKDS QICELKYDKQ IDLSTVDLKK LRVKELKKILDDWGETCKGC AEKSDYIRKI NELMPKYAPK AASARTDL

Storage & Handling

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StorageStore at 4°C for up to two weeks. For long term storage, aliquot and store at -20°C, avoid freeze/thaw cycles.
Buffer/PreservativesLyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris, 300 mM NaCl, 3 mM beta -mercaptoethanol, pH 8.5
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

Alternative Names

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Murine Cardiotrophin1 protein
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Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
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SDS-PAGE
Sodium Dodecyl Sulphate PolyAcrylamide Gel Electrophoresis
View Protocol
HPLC
High-Performance Liquid Chromatography
View Protocol

Available Sizes

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10 μg
$ 340.00
100 μg
$ 1,480.00
500 μg
$ 3,300.00
DispatchUsually dispatched within 2-3 weeks
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