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Human IL-23R Protein, Fc Tag

SKU: orb570284
ActiveBiologically Active

Description

Human IL-23 R, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Gly 24 - Gly 355 (Accession # Q5VWK5-1).

Research Area

Disease Biomarkers

Images & Validation

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Application Notes
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 64.5 kDa. The protein migrates as 90-100 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression SystemHEK293
Biological OriginHuman
Biological ActivityCaptured Human IL-23 R, Fc Tag on CM5 chip via anti-human IgG Fc antibodies surface can bind Human IL23A & IL12B, His Tag with an affinity constant of 5.36 nM as determined in a SPR assay (Biacore T200) (Routinely tested).
TargetIL-23R
ReactivityHuman
TagC-Fc
Expression RegionGly 24 - Gly 355
Endotoxins1.0 EU per μg
ConjugationUnconjugated
MW64.5 kDa
Purity95%
Protein SequenceNP_653302.2

Storage & Handling

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Storage-20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
Form/AppearancePowder
Buffer/PreservativesTris with Glycine, Arginine and NaCl, pH 7.5
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

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UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
View Guide

Available Sizes

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100 μg
$ 750.00
1 mg
$ 4,480.00
DispatchUsually dispatched within 5-10 working days
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