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Human IL-12 R beta 1 Protein, Fc Tag

SKU: orb570282
ActiveBiologically Active

Description

Human IL-12 R beta 1, Fc Tag is expressed from human 293 cells (HEK293). It contains AA Cys 24 - Glu 540 (Accession # P42701-1).

Research Area

Disease Biomarkers

Images & Validation

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Application Notes
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 83.5 kDa. The protein migrates as 95-110 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Key Properties

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Expression SystemHEK293
Biological OriginHuman
Biological ActivityHuman IL-12 R beta 1, Fc Tag captured on CM5 chip via Anti-human IgG Fc antibodies surface can bind Human IL-12B & IL-12A Heterodimer Protein, His Tag & Flag Tag with an affinity constant of 2.06 nM as determined in a SPR assay (Biacore T200) (Routinely tested).
TargetIL-12 R beta 1
ReactivityHuman
TagC-Fc
Expression RegionCys 24 - Glu 540
Endotoxins1.0 EU per μg
ConjugationUnconjugated
MW83.5 kDa
Purity90%
Protein SequenceNP_005526.1

Storage & Handling

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Storage-20°C to -70°C for 12 months in lyophilized state;. -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower
Form/AppearancePowder
Buffer/PreservativesPBS, pH 7.4
Expiration Date6 months from date of receipt.
DisclaimerFor research use only

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    Recombinant Human IL-12RB1/IL-12 R beta 1/IL-12RB Protein is produced by Human Cells expression system. The target protein is expressed with sequence (Cys24-Glu540) of human IL-12RB1/IL-12 R beta 1/IL-12RB (Accession #P42701) fused with an Fc tag at the C-terminus.

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UniProt Details

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No UniProt data available

NCBI Reference Sequences

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Associated Accession Numbers
Curated reference sequences for the gene transcript and protein product

Protocol Information

Protein Handling and Storage Guide
Protein Handling Guide
View Guide

Available Sizes

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100 μg
$ 660.00
1 mg
$ 3,860.00
DispatchUsually dispatched within 5-10 working days
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