HER4/ERBB4 Protein, Human, Recombinant (His & Avi)

SKU: orb1960446

Description

Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS. HER4/ERBB4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 72.7 kDa and the accession number is Q15303-1.

Research Area

,Recombinant-Protein

Images & Validation

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Application Notes	Reconstitute the lyophilized protein in distilled water. The product concentration should not be less than 100 μg/ml. Before opening, centrifuge the tube to collect powder at the bottom. After adding the reconstitution buffer, avoid vortexing or pipetting for mixing.

Key Properties

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Expression System	HEK293 Cells
Biological Origin	Human
Biological Activity	Her4, a member of the EGF receptor family, plays a variety of roles in physiological and pathological states. Genetic studies have indicated a link between Her4 and type 2 diabetes and obesity. Her4 may play an important role in glucose homeostasis and lipogenesis. Her4 deficiency-related obesity and adipose tissue inflammation may contribute to the development of MetS. HER4/ERBB4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 72.7 kDa and the accession number is Q15303-1.
Tag	C-His-Avi
Expression Region	Gln26-Pro651
MW	72.7 kDa (predicted). Due to glycosylation, the protein migrates to 80-110 kDa based on Tris-Bis PAGE result.
Purity	98.00%

Storage & Handling

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Storage	-20°C
Expiration Date	6 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

UniProt

Q15303

UniProt Details

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No UniProt data available

Protocol Information

Protein Handling and Storage Guide

Protein Handling Guide

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