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Amyloid 17-42

SKU: orb1981051

Description

Amyloid 17-42 (Aβ(17-42)), a significant component of diffuse plaques in Alzheimer's disease and cerebellar pre-amyloid in Down's syndrome, results from alpha- and gamma-secretase cleavage of amyloid precursor protein (APP) and can trigger neuronal apoptosis via the Fas-like/caspase-8 activation pathway [1].

Images & Validation

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Key Properties

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CAS Number155178-13-5
MW2577.05
Purity98.00%
FormulaC119H194N28O33S
SMILES[C@H](CC1=CC=CC=C1)(C(N[C@@H](CC2=CC=CC=C2)C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)C)=O)[C@H](CC)C)=O)[C@H](C)C)=O)C(C)C)=O)=O)=O)[C@@H](C)C)=O)CCSC)=O)CC(C)C)=O)=O)[C@H](CC)C)=O)[C@H](CC)C)=O)C)=O)=O)CCCCN)=O)CC(N)=O)=O)CO)=O)=O)[C@@H](C)C)=O)CC(O)=O)=O)CCC(O)=O)=O)C)=O)=O)NC([C@@H](NC([C@H](CC(C)C)N)=O)[C@@H](C)C)=O

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

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No computed properties available.

Protocol Information